The Real Cause of Perimenopause Fatigue & Pain

Jan 19, 2026

Ask episode

Chapters

Transcript

Episode notes

What if your chronic fatigue, fibromyalgia, or overwhelming perimenopause symptoms aren't just hormonal, but neurological?

I'm Dr. Betty Murray, and in this groundbreaking episode, I sit down with Ashok Gupta, founder of the Gupta Program and pioneer in neuroplasticity-based brain retraining for chronic illness. Ashok's personal journey from debilitating chronic fatigue syndrome at Cambridge University to complete recovery led him to develop a program that has now been validated in seven clinical studies and helps thousands of people worldwide rewire their nervous systems to heal.

You'll Discover:

● Why 85% of chronic fatigue, fibromyalgia, and mast cell activation cases occur in women aged 35-60, and how perimenopause creates a "drought in the kingdom" that sensitizes the nervous system

● How your immune system and nervous system become traumatized after fighting off threats and keep firing weapons of war even after the battle is over, causing widespread inflammation

● Why survival is the number one priority of your brain, and how it would rather trigger your immune and nervous systems wildly to protect you than bring you back to balance

● How neuroplasticity works through repetition and intensity to rewire the brain, just like learning to drive a car transforms from conscious effort to automatic behavior

● Why estrogen loss in perimenopause builds more brain receptors (not less), affects the cannabinoid system and mitochondrial function in the prefrontal cortex, making the nervous system hypersensitive to fluctuations

● The neuroimmune conditioned syndrome framework covering symptoms like poor sleep, pain, fatigue, swollen glands, temperature fluctuations, post-exertional malaise, and cognitive dysfunction across multiple mysterious illnesses

● How the Gupta Program was four times more effective than sleep advice, diet, supplements, and activity recommendations for long COVID fatigue in independent studies

● Why modern medicine treats hardware problems (broken bones) well but fails at software problems (nervous system dysregulation) that account for 50% of doctor visits

PLUS, we talk about the first-ever clinical study on perimenopause and menopause using the Gupta Program, and you can participate!

This episode is for women experiencing chronic fatigue, fibromyalgia, long COVID, anxiety, or overwhelming perimenopause symptoms that medications haven't helped. If you're tired of being told "it's just stress" or "it's all in your head," this conversation will change everything.

Watch now and discover how retraining your brain can heal your body, and how you can participate in groundbreaking research.

Connect with Ashok Gupta:

Website: GuptaProgram.com

Gupta Program App (free downloads available on App Store and Play Store)

Connect with Dr. Betty Murray:

Betty Murray Website: https://www.bettymurray.com/

Instagram: https://www.instagram.com/drbettymurray/

Links:

The Fierce Female Method for Longevity (Dr. Betty's book): https://fierce.hormoneshelp.com/

Menrva Telemedicine: https://gethormonesnow.com/

FREE Hormone Quiz: https://bit.ly/3wNJOec Living Well Dallas: https://www.livingwelldallas.com/

Hormone Reset: https://hormonereset.net/