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JAMA Editors' Summary

Adding Tirzepatide vs Prandial Insulin to Basal Insulin, Beta-Blockers in Septic Shock, USPSTF on Oral Health Screening, and more

Nov 7, 2023
This podcast discusses topics such as the efficacy of Chrysepatide and Insulinless Pro in Type 2 diabetes, the use of Landial Lald in Septic Shock, alcohol use disorder therapies, AI in radiology, sepsis management, drug price negotiations, prevention research, oral health screening, non-alcoholic fatty liver disease management, health equity in AI tools, and climate change's impact on mental health in Africa.
12:19

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Quick takeaways

  • Tirzepatide demonstrated better outcomes in Type 2 diabetes compared to Insulinless Pro.
  • Oral naltrexone and acamprosate showed promise in treating alcohol use disorder.

Deep dives

Chrysepatide vs. Insulinless Pro in Type 2 Diabetes

A Phase 3 clinical trial compared the efficacy and safety of Chrysepatide and Insulinless Pro as adjunctive therapies to basal insulin in Type 2 diabetes. Chrysepatide showed a statistically significant improvement in hemoglobin A1C levels, less hypoglycemia, and more reduction in body weight compared to Insulinless Pro.

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