Science Weekly
Secrets of ageing: what makes me age?
Jul 30, 2024
In this insightful discussion, Richard Faragher, a professor of biogerontology at the University of Brighton, shares his expertise on the biology of aging. He explores the evolutionary mechanisms that shape our lifespans and the fascinating link between aging and diseases. Faragher delves into innovative interventions to slow aging and emphasizes the significance of lifestyle choices in extending life. With a blend of humor and science, he raises thought-provoking questions on how society might adapt to an aging population.
20:49
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Quick takeaways
- Aging is characterized by biological hallmarks like cell senescence and genomic instability, which contribute to increased disease likelihood over time.
- Theories such as mutation accumulation and disposable soma explain aging's evolutionary significance, prioritizing reproduction over long-term somatic maintenance.
Deep dives
Understanding Aging Mechanisms
Aging is a complex biological process characterized by intrinsic mortality, which significantly increases the likelihood of diseases as one ages. Researchers identify 'aging hallmarks' such as cell senescence and genomic instability that contribute to the biological aging process. For instance, as cells divide, the protective telomeres at the end of chromosomes shorten, which is a hallmark of aging leading to cellular dysfunction. Understanding these mechanisms allows scientists to examine potential interventions to slow down aging and improve overall health in later years.
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