Science Weekly Secrets of ageing: what makes me age?
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Jul 30, 2024 
In this insightful discussion, Richard Faragher, a professor of biogerontology at the University of Brighton, shares his expertise on the biology of aging. He explores the evolutionary mechanisms that shape our lifespans and the fascinating link between aging and diseases. Faragher delves into innovative interventions to slow aging and emphasizes the significance of lifestyle choices in extending life. With a blend of humor and science, he raises thought-provoking questions on how society might adapt to an aging population.
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Exponential Rise in Mortality
- Mortality risk increases exponentially with age, defining biological aging rather than extrinsic causes like accidents. - Aging is the biological process that raises the chance of disease and death as we get older.
Defining Aging Mechanisms
- Aging mechanisms must actively affect bodies and influence aging rate when sped up or slowed down. - Researchers have identified 9 or 10 such hallmarks but expect more to be found.
The Trouble with Senescent Cells
- Senescent cells stop dividing and cause damage by altering protein production and inducing inflammation. - Aging immune systems clear these cells less effectively, causing accumulation and harm.