Why Estrogen HRT Can Backfire When your Toxic Bucket is Full | Solo

Dec 20, 2025

Explore how hormones interact with a toxic environment and why adding estrogen can backfire. Discover the hidden dangers of xenoestrogens in everyday products and their impact on health. Learn about the effects of air pollution on hormones and fat loss. Discuss practical steps to reduce toxic burden at home, from avoiding harmful beauty products to using air filters. This insightful conversation challenges traditional views on hormone therapy by highlighting the importance of metabolic and liver health.

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INSIGHT

Estrogen Into A Toxic Soup Backfires

Estrogen replacement can misbehave when introduced into a body with high toxic burden and impaired clearance pathways.
Xenoestrogens in the environment make tissues behave as if estrogen dominance exists even without high endogenous estrogen.

ANECDOTE

Influencer Perfume Moment Sparked This Episode

Dr. Tyna Moore describes watching an influencer douse herself in perfume and wearing heavy makeup and dye, which highlighted toxic-soup blind spots.
She uses this example to stress that visible beauty routines often increase hidden toxic burden.

ADVICE

Make Estrogen The Last Step

Do not start estrogen until metabolic health, liver function, bowel regularity, sleep and strength training are addressed.
Use an integrative hierarchy so estrogen is the last hormone introduced, not the first.

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Everyone wants to talk about hormones right now. Estrogen, HRT, menopause, fixes. What almost no one is talking about is the environment those hormones are being dropped into. In this episode, I break down what happens when estrogen enters a body with a high toxic load, and why hormone therapy can backfire when your detox pathways, liver, and metabolic health are compromised. We talk about xenoestrogens, fake estrogens from everyday exposures like fragrance, plastics, air pollution, and household products, and how they hijack estrogen receptors, disrupt progesterone balance, and drive symptoms that get mislabeled as “hormone problems.”

This is a practical, reality-based conversation about toxic burden, not detox fantasies. If you are on HRT, considering it, struggling with stubborn symptoms, or wondering why your body feels stuck despite doing everything “right,” this episode fills in the missing piece most hormone conversations ignore.

Topics Discussed:

→ How does air pollution affect hormones?

→ Can toxins cause estrogen dominance?

→ Does poor air quality impact fat loss?

→ Are air filters worth it for health?

→ How do xenoestrogens disrupt metabolism?

On This Episode We Cover:

→ 00:00 - Introduction

→ 01:52 - Hidden toxins in beauty products

→ 05:49 - The toxic bucket explained

→ 09:58 - Estrogen pills & patches risks

→ 15:37 - Understanding estrogen dominance

→ 19:41 - Detox strategies you can use

→ 22:37 - Common xenoestrogens around you

→ 28:13 - Microplastics, pesticides & parabens

→ 32:55 - Airborne toxins & your health

→ 37:01 - Adhesives, paint & laundry hazards

→ 43:25 - Pest control & pets

→ 48:40 - Outdoor air pollution impacts

→ 52:38 - Control the controllables

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Show Links:

→ Jaspr | https://jaspr.co/DRTYNA, code DRTYNA for the best sale of the year!

→ AquaTru | Go to https://aquatruwater.com/?oid2=50&affid2=2320 and discount will apply at checkout.

→ Holiday Gift Guide

Further Listening:

→ EP. 238:You Need to Become an Air Snob Because Mold Happens | CEO Mike Feldstein of Jaspr

→ EP. 175: Air Quality, Mold and Autoimmune Issues The Hidden Links | with CEO Mike Feldstein of Jaspr

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.