
The Dr. Lee Warren Podcast When the Thing Won't Go Away (S12E94)
Nov 21, 2025
Explore the journey of overcoming persistent challenges like chronic illness and relationships. Discover the concept of persistent problem palliation—shifting from the pursuit of a cure to altering your perspective. Learn the neuroscience behind chronic pain and the importance of resilience through gratitude practices. Engage in daily rituals that foster hope and invert illness inertia. Additionally, uncover how suffering can lead to growth and redefine your relationship with adversity.
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Pain Is Often A Memory
- Chronic problems often persist because the brain remembers pain rather than ongoing injury.
- Reframing the relationship to the problem can reduce suffering even when the cause is unchanged.
Personal Loss Led To Perspective Shift
- After losing his son, Lee Warren had to accept that the situation was unchangeable and shift perspective.
- That acceptance led to practicing trust and finding purpose despite ongoing pain.
Hardship Builds Neural Resilience
- Surviving hardship strengthens neural circuits for future resilience via the anterior cingulate cortex.
- Doing hard things intentionally lowers resistance for subsequent difficult actions.


