Barbell Shrugged

Physiology Friday: [THYROID] Function, Dysfunction, Brain Chemistry, and Autoimmunity w/ Anders Varner, Doug Larson, Travis Mash and Dan Garner

May 23, 2025
Dive into the fascinating world of thyroid health! Learn how this gland impacts weight gain and performance. Discover the intricate connections between the thyroid, hypothalamus, and pituitary gland. Explore the role of gut health and vitamin A on thyroid function. Uncover how birth control can influence thyroid levels and the essence of T3 for muscle growth. Plus, investigate the thyroid's significant role in regulating menstrual cycles and brain chemistry. A deep dive into diagnosis and holistic health awaits!
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INSIGHT

Thyroid Hormone Regulation Axis

  • The thyroid is controlled by the hypothalamus-pituitary-thyroid axis which regulates thyroid hormone production.
  • T4 is mostly produced and converted to the active T3 form, which acts on tissues throughout the body.
INSIGHT

Lifestyle Influences Thyroid Signaling

  • Inflammation, dopamine levels, cortisol, and gut bacteria toxins can disrupt thyroid signaling.
  • Many thyroid dysfunction cases are influenced by lifestyle factors affecting hormone signals, not just the thyroid itself.
INSIGHT

Binding Proteins and Gut Impact

  • Thyroid hormone binding proteins produced in the liver can trap hormones, reducing their availability.
  • Gut health strongly affects T4 to T3 conversion, impacting thyroid function even with normal lab tests.
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