Data in Biotech

Modernizing Clinical Data Analysis with Jesse Paquette

8 snips
Jul 11, 2025
Guest
Jesse Paquette
In this engaging discussion, Jesse Paquette, Co-founder and Chief Science Officer of Tag.bio, delves into the game-changing impact of data mesh architecture and FAIR data principles on clinical workflows. He reveals how Tag.bio empowers researchers to navigate legacy system challenges and embrace AI-readiness. Key topics include the importance of harmonized data for efficient clinical trials and how smaller biotech firms can leverage Tag.bio's agile platform for faster, more effective data-driven decisions.
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ANECDOTE

Jesse Paquette's Career Journey

  • Jesse Paquette shares his diverse background spanning academia and industry before founding TagBio.
  • His experience includes computational biology at UCSF and topological data analysis at a Silicon Valley startup.
INSIGHT

Data Mesh Powers TagBio Platform

  • TagBio uses a data mesh approach treating data as a rigorously managed product with versioning.
  • This enables FAIR data principles, harmonization, and independent data products with APIs for researchers.
ADVICE

Handle Legacy Data Carefully

  • Address legacy infrastructure by creating versioned snapshots of clinical and biomarker data.
  • Harmonize all disparate datasets and use controlled vocabularies to prepare data for AI.
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