Data in Biotech

Dr. Aliza Apple, VP of Catalyze360 AI/ML at Eli Lilly, joins Ross Katz to unveil TuneLab—a first-of-its-kind federated learning platform accelerating preclinical drug discovery. Learn how Lilly’s billion-dollar models are empowering early-stage biotechs, the science behind federated learning, and what this means for the future of pharmaceutical R&D. ​​What You'll Learn in This Episode: >> How Eli Lilly's TuneLab democratizes access to proprietary AI models trained on decades of pharmaceutical data >> What federated learning means for IP protection and collaborative data sharing in biotech >> Which two key use cases are driving TuneLab’s impact today: small molecule ADME and antibody developability >> How TuneLab’s early adopters like Firefly Bio and Superluminal are shaping the platform’s evolution >> Why generalizability—not just accuracy—is the true power of collaborative AI in drug development Meet Our Guest Dr. Aliza Apple is VP of Catalyze360 AI/ML at Eli Lilly and a biotech trailblazer with deep roots in AI-driven drug discovery. She has led initiatives from founding startups to heading Lilly Gateway Labs and now pioneers innovation at the intersection of data and biotech. About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyConnect with Aliza Apple  on LinkedIn  Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!Connect with Ross Katz on LinkedIn Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

In this episode of Data in Biotech, host Ross Katz talks with Jesper Ryge, Director of Computational Biology at Merck Germany. Jesper shares his journey from neuroscience labs to leading computational teams, offering deep insights into disease modeling, target discovery, and multi-omics integration. Discover how AI and spatial transcriptomics are shaping the future of pharma R&D. ​​What You'll Learn in This Episode >> How single-cell and spatial transcriptomics enhance disease mechanism discovery >> Why data integration and knowledge graphs are critical for target validation >> How computational biology teams interface with wet lab research >> What makes Merck Germany's data strategy unique in biotech >> How generative AI is changing how pharma interprets complex datasets Meet Our Guest Jesper Ryge is Director of Computational Biology at Merck Germany. A biophysicist by training, he brings deep expertise in neuroscience, single-cell analysis, and bioinformatics to pharmaceutical R&D. About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about MerckConnect with Jesper Ryge on LinkedIn  Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!Connect with Ross Katz on LinkedIn Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

To mark our 50th episode, host Ross Katz brings back three visionary leaders—Dave Johnson (Dash Bio), Wolfgang Halter (Merck Life Science), and Jacob Oppenheim (RAVen)—together for a reflection on the evolution of biotech. They unpack the realities behind AI hype, the future of data-driven innovation, and what’s really changing in drug development. ​​What You'll Learn in This Episode: >> Where real innovation is emerging across startups, big tech, and academia >> The biggest misconceptions about data in biotech—and why they persist >> What it takes to build trust in AI-powered biotech tools >> Why progress in biotech depends as much on execution as it does on breakthroughs >> How industry veterans see the future of automation, regulation, and global competition Meet Our Guests Dave Johnson is CEO and Co-Founder of Dash Bio and former Chief Data & AI Officer at Moderna. He’s pioneering automation in clinical bioanalysis to accelerate drug development. Wolfgang Halter leads Data Science at Merck Life Science, developing tools like BayBE to optimize R&D through smarter data modeling and open-source innovation. Jacob Oppenheim is a Venture Partner at RAVen and co-founder of Fresnel. With a PhD in Biological Physics, he champions the transition to digital-native biopharma. About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyConnect with Dave Johnson  on LinkedIn Connect with Wolfgang Halter on LinkedInConnect with Jacob Oppenheim on LinkedIn Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!Connect with Ross Katz on LinkedIn Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

In this episode of Data in Biotech, Yaron David, CTO and Co-Founder of BioRaptor, joins host Ross Katz to explore how biotech companies can gain a holistic view of bioprocessing through real-time data integration, visualization, and modeling. Learn how BioRaptor’s full-stack platform helps scientists replace clunky spreadsheets with actionable insights—accelerating experiments and optimizing yields. ​​What You'll Learn in This Episode: >> Why Excel is holding back innovation in bioprocessing labs >> How BioRaptor enables holistic bioprocess understanding across experiments >> The role of virtual sensors in enhancing real-time data visibility >> How BioRaptor drives ROI by onboarding customers in weeks, not months >> The difference between operational and optimization AI in biotech Meet Our Guest Yaron David is CTO and Co-Founder of BioRaptor, an AI-powered analytics platform transforming bioprocess data into scientific insights. With an MD and PhD in neuroscience, he blends medical, software, and startup experience to revolutionize data infrastructure for biotech. About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about BioRaptorConnect with Yaron David on LinkedIn  Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!Connect with Ross Katz on LinkedIn Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

In this engaging discussion, Jesse Paquette, Co-founder and Chief Science Officer of Tag.bio, delves into the game-changing impact of data mesh architecture and FAIR data principles on clinical workflows. He reveals how Tag.bio empowers researchers to navigate legacy system challenges and embrace AI-readiness. Key topics include the importance of harmonized data for efficient clinical trials and how smaller biotech firms can leverage Tag.bio's agile platform for faster, more effective data-driven decisions.

Kenny Workman, co-founder and CTO of LatchBio, discusses transforming biotech's data infrastructure. He highlights the urgent need for scalable systems in spatial biology and the challenges faced when adapting to new technologies. Kenny explains LatchBio's five core components that streamline molecular data processing and the importance of effective collaboration across disciplines. He also explores the impact of large language models on public data curation and the industry's shift towards data-driven research, emphasizing the importance of better tech adoption.

Entrepreneur Jeremy Shane joins host Ross Katz to discuss Life for Health, a revolutionary framework aiming to tackle chronic disease through the integration of life insurance, longitudinal data, and preventative care.  From drug discovery feedback loops to outcomes-based pricing, Shane outlines a bold new path for biotech and healthcare convergence. ​​What You'll Learn in This Episode: Why today's healthcare system fails chronic disease patients and how Life for Health aims to fix it.How longitudinal data and life insurance can realign healthcare incentives for better outcomes.The economic logic behind outcomes-based annuity pricing for breakthrough drugs like GLP-1s.What biotech companies gain from a proactive, participant-driven health model.How clinical trials could transform through pre-qualified data-rich populations. Meet Our Guest Jeremy Shane, Venture Partner at NextGen Venture Partners, is a healthcare innovator focused on chronic disease. With leadership experience at HealthCentral, WebMD, and 2U, he now pioneers Life for Health, blending life insurance with preventative care to realign incentives and extend health span. Life for Health, the book, will be released in July 2025.  To learn more about Life For Health or get involved, go to www.lifeforhealth.com About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyConnect with Jeremy Shane on LinkedIn or on Twitter @jeremylshane Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode! Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

In this episode of Data in Biotech, host Ross Katz sits down with Scott Lipnick, Co-Founder and President of Etiome, to explore how preemptive medicine is changing the way biotech approaches therapeutic modeling and intervention.  Discover how Etiome’s recently launched, AI-driven platform is built to detect disease earlier, identify precise biomarkers, and create stage-specific treatments—all before symptoms arise.  It’s a visionary approach to healthcare focused on preserving health, not just managing illness. What You'll Learn in This Episode: Why Scott Lipnick believes the future of medicine lies in preemptive care.How Etiome uses AI to map disease progression at the cellular level.The role of biomarkers in identifying disease before symptoms surface.How Etiome applies its Temporal Biodynamics platform across diseases.What venture creation looks like at Flagship Pioneering. Meet Our Guest Scott Lipnick is the Co-founder and President of Etiome. At the forefront of preemptive medicine, Scott’s work focuses on predicting disease progression and delivering personalized, early-stage interventions using cutting-edge AI and molecular tools. About The Host Ross Katz is Principal and Data Science Lead at CorrDyn. Ross specializes in building intelligent data systems that empower biotech and healthcare organizations to extract insights and drive innovation. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about EtiomeConnect with Scott on LinkedIn Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode! Sponsored by… This episode is brought to you by CorrDyn, the leader in data-driven solutions for biotech and healthcare. Discover how CorrDyn is helping organizations turn data into breakthroughs at CorrDyn.

In this episode of Data in Biotech, host Ross Katz speaks with Patrick Torbey, CEO and Co-Founder of Neoplants, about using genetic engineering and microbiome innovation to tackle indoor air pollution. Patrick explains how Neoplants is turning everyday houseplants into powerful air purifiers using synthetic biology, offering insights into VOC degradation, enzyme pathways, and data-driven R&D. ​​What You'll Learn in This Episode: How genetically modified plants and microbiomes can reduce indoor air pollution by targeting VOCs like formaldehyde and benzeneThe scientific and engineering challenges of modifying indoor plants at the genomic levelWhy data-driven testing and simulation are critical to optimizing plant function and user impactThe role of synthetic biology in creating sustainable, scalable biotech productsPatrick’s vision for solving climate challenges through engineered plant ecosystems ​​Meet Our Guest: Patrick Torbey is the CEO and Co-Founder of Neoplants, a Paris-based biotech startup engineering plants to purify indoor air. With a PhD in genetic editing and deep expertise in synthetic biology, Patrick leads Neoplants in building functional, aesthetically unique, and sustainable plant systems for the future. About The Host: Ross Katz is the Principal Data Scientist at CorrDyn. He brings decades of experience across biotech, energy, and non-profit sectors, with a focus on building smarter data systems, machine learning pipelines, and actionable insights for complex industries. Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about NeoplantsConnect with Patrick Torbey on LinkedIn Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode!

Phage therapy is stepping into the spotlight as antibiotic resistance rises - and Jessica Sacher is helping lead the charge. In this episode, Ross Katz speaks with Jessica, Co-Founder of Phage Directory and Staff Scientist at Stanford, about sourcing phages, operationalizing therapy, and predicting efficacy through data. This conversation explores how personalized phage therapy works, its scalability, and the data challenges shaping its future. ​​What You'll Learn in This Episode: Why phage therapy is a promising solution to antibiotic-resistant infectionsHow Phage Directory connects researchers and clinicians to accelerate treatmentWhat operational hurdles exist in scaling personalized phage productionHow data science is being applied to predict effective phage-bacteria matchesWhy building infrastructure and awareness is essential to adoption in clinical care Connect with Our Guest: Sponsor: CorrDyn, a data consultancyFind out more about Phage DirectoryConnect with Jessica on LinkedIn Connect with Us: Follow the podcast for more insightful discussions on the latest in biotech and data science.Subscribe and leave a review if you enjoyed this episode! Resources Mentioned:  Why Language Itself Might Be Holding Back AI – by Ross Katz: https://www.linkedin.com/pulse/why-language-itself-might-holding-back-ai-ross-katz-rcl9e/?trackingId=Y6%2FH45W%2BxImfl%2By2geB6%2Bg%3D%3DBacteriophage Therapy for Multidrug-Resistant Infections – PubMed: https://pubmed.ncbi.nlm.nih.gov/40026251/Cystic Fibrosis Australia and Phage Australia Survey – medRxiv: https://www.medrxiv.org/content/10.1101/2024.05.14.24307275v1Phage Directory: https://phage.directory/