Something You Should Know

How Ozempic and Similar Weight Loss Drugs Really Work & The Story of Money

29 snips
Jan 5, 2026
Aimee Donnellan, a columnist and author focusing on Ozempic, delves into how GLP-1 weight-loss drugs work, their potential risks, and the significant impact on obesity treatment. She reveals the drug's biological effects on hunger and cravings and discusses the implications of discontinuation. Meanwhile, David McWilliams, a former central bank economist, explores the fascinating history of money as a social technology, its role in civilization, and the psychological influences it has on our lives. Both guests provide deep insights into contemporary issues affecting health and wealth.
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INSIGHT

Mental Rehearsal Helps Trained Skills

  • Imagining actions sends weak signals to muscles and can improve performance for practiced skills.
  • Mental rehearsal fails for novices because it encodes incorrect technique.
INSIGHT

GLP-1 Drugs Mark A Breakthrough

  • GLP-1 drugs like Ozempic are seen by obesity specialists as a major breakthrough.
  • Researchers still study brain effects and long-term systemic benefits beyond weight loss.
INSIGHT

GLP-1 Is A Natural Fullness Signal

  • GLP-1 is a natural gut hormone that signals fullness by delaying stomach emptying.
  • Novo Nordisk developed injectable versions originally for type 2 diabetes and discovered weight loss effects.
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