785 Tyler Smith: Founder & CEO of Hundred

On today’s episode, Kara welcomes Tyler Smith, Founder and CEO of Hundred — the innovative health platform turning personalized data into real, measurable transformation.

Tyler’s story is as compelling as it is inspiring. After discovering that his biological age was eight years older than his chronological age, he made a life-altering decision: invest in the world’s top physicians, build a private longevity lab, and completely reengineer his health. The result? He reversed his biological age by an astounding 15 years — and uncovered just how broken and inaccessible personalized health optimization has been for everyday people.
That breakthrough became the foundation for Hundred, a fully integrated health platform that merges blood work, wearables, medical history, AI, and guidance from top clinicians into a clear, evidence-based 100-day action plan. Before launching Hundred, Tyler built and sold SkySlope for a reported $80M, and he now brings that same focus, rigor, and obsession with outcomes to transforming how we approach our health.
In this episode, Tyler shares what drove him to build Hundred, the gaps he saw in traditional and DTC testing models, and why knowing your data is only half the battle — the real power lies in turning insight into action. He opens up about his own transformation, the science behind the platform, and what it takes to build a company at the intersection of longevity, technology, and human performance.
A must-listen for anyone passionate about proactive health, entrepreneurship, or building a life with intention.

Are you interested in sponsoring and advertising on The Kara Goldin Show, which is now in the Top 1% of Entrepreneur podcasts in the world? Let me know by contacting me at karagoldin@gmail.com. You can also find me @‌KaraGoldin on all networks.

To learn more about Tyler Smith and Hundred:
https://www.hundred.com
https://www.instagram.com/hundred
https://www.linkedin.com/company/hundred

Sponsored By:

RULA - Go to Rula.com/KARAGOLDIN for convenient therapy that’s covered by insurance.

LinkedIn Jobs - Head to LinkedIn.com/KaraGoldin to post your job for free.

Check out our website to view this episode’s show notes: https://karagoldin.com/podcast/785