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The First Pig to Human Kidney Transplant
May 2, 2024
Mike Curtis, CEO of eGenesis, discusses genetically engineering pigs for human organ transplants. They explore using CRISPR technology to edit pig genomes, adding human genes for regulatory factors. Ethical considerations and future potential of pig organs in transplants are also highlighted.
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Quick takeaways
- Advancements in genetic engineering enable cross-species transplants with inactivated retroviruses.
- CRISPR technology contributes to editing pig genomes for enhanced human organ compatibility.
Deep dives
Genetically Engineered Pig Organs for Human Patients
Advancements in genetic engineering have led to groundbreaking medical breakthroughs in creating genetically engineered pig organs for human transplant. Researchers have successfully inactivated porcine retroviruses, addressing immune system rejection concerns in cross-species transplants. CRISPR technology plays a pivotal role in editing pig genomes to enhance organ compatibility, with the vision of ultimately creating organs that do not require immunosuppression. The case of Rick Flayman, who received a genetically engineered pig kidney transplant and responded positively, highlights the potential for saving lives through innovative organ transplantation techniques.
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