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Mayo Clinic Talks

Osteoporosis, Fragility & Bone Health Edition | “Stiffen Up” Management of Osteoporosis

Oct 26, 2023
In this podcast, Kurt A. Kennel, M.D., discusses the treatment options for osteoporosis, emphasizing the importance of preventing fractures. They explore the role of calcium and vitamin D, potential side effects of medications, and the importance of good oral hygiene. The podcast also highlights the key points in managing osteoporosis, including fall prevention, nutrition, exercise, and continuously assessing treatment choices.
21:33

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Bisphosphonates are considered first-line therapy for osteoporosis and work by suppressing bone breakdown, with options for oral or infusion treatment and recommended drug holidays to maintain bone resorption balance.
  • Anabolic agents are a newer class of drugs that stimulate bone-building cells to work faster, and can be considered for severe osteoporosis or multiple fractures. After anabolic therapy, individuals usually transition to anti-resorptive medications to maintain bone density.

Deep dives

Goal of Osteoporosis Treatment: Preventing Fractures

The goal of treating osteoporosis is to prevent fractures and the resulting complications, such as chronic pain and disability. Treatment options like bone density tests aid in identifying those at risk, but the focus remains on avoiding fractures. Calcium and vitamin D supplements are recommended, with targets of around 1,000 milligrams of calcium per day and 20 to 25 micrograms of vitamin D. Bisphosphonates are considered first-line therapy and work by suppressing bone breakdown. They can be taken orally for five years or via infusion for three years. Drug holidays may be recommended to maintain a healthy balance in bone resorption. It is important to prioritize oral health to minimize the risk of complications such as osteonecrosis of the jaw.

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