#124 - AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more
Aug 17, 2020
Dive into real-world case studies on metabolic dysregulation, low testosterone, and menopause. Discover why timing supplements is crucial for lab test accuracy. Uncover the significance of family medical history in identifying health risks. Learn about the oral glucose tolerance test's impact and how factors like sleep and alcohol influence testosterone levels. Each case reveals insights into metabolic health, including high cholesterol and elevated uric acid, making complex health issues relatable and understandable.
16:49
forum Ask episode
web_stories AI Snips
view_agenda Chapters
auto_awesome Transcript
info_circle Episode notes
volunteer_activism ADVICE
Supplement Timing for Lab Tests
Stop taking most supplements before lab tests to get accurate results.
Consider how long a supplement takes to affect the body before testing.
volunteer_activism ADVICE
Accurate Supplement Tracking
Check with patients about supplement usage one month before lab tests.
Postpone tests if they recently stopped to ensure accurate biomarkers.
volunteer_activism ADVICE
Detailed Family History
Gather comprehensive family history data from patients, including lifestyle context.
Give patients templates beforehand, as recalling details on the spot is difficult.
Get the Snipd Podcast app to discover more snips from this episode
As a follow up to AMA #14 where Peter explained his framework for analyzing labs, this “Ask Me Anything” (AMA) episode focuses on a number of real-world case studies exploring metabolic dysregulation, low testosterone, menopause, hypothyroidism, elevated uric acid, and more. From the examples discussed, you can follow along how our clinical team goes about interpreting diagnostic measures and applying relevant research findings. Once again, Bob Kaplan, Peter’s head of research, will be asking the questions. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #15 show notes page.
We discuss:
Should you stop taking supplements before getting a lab test? [2:45];
Family history—Questions to ask and what to look for [5:30];
The purpose of an oral glucose tolerance test (OGTT) [12:15];
Case study—Insufficient muscle mass for proper glucose disposal [17:15];
Why hemoglobin A1c is a relatively unhelpful metric [24:00];
Case study—Exceeding carbohydrate tolerance [26:30];
Case study—Metabolic dysfunction and a framework for metabolic health [33:30];
Peter’s ideal tracking of metabolic health for all his patients [43:30];
Contrasting presentations of hypogonadism—Low free testosterone [45:00];
How sleep, exercise, and alcohol affect testosterone levels? [56:20];
Case study—Surprisingly fast onset of menopause [59:25];
Case study—Hypothyroidism and high cholesterol [1:07:00];
Case study—Elevated uric acid and hypertension [1:10:55]; and
The Peter Attia Drive