The Curbsiders Internal Medicine Podcast

#346 Meningitis

7 snips
Jul 25, 2022
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ADVICE

When In Doubt, Do The LP

  • If you are even considering a lumbar puncture, do the LP because the result (positive or negative) will change management.
  • A negative LP can be as clinically valuable as a positive one when patients are already on multiple antimicrobials.
ADVICE

Get Blood Cultures Then Start Antibiotics

  • Obtain blood cultures before antibiotics because ~50% of bacterial meningitis patients have bacteremia and cultures can guide therapy and duration.
  • Start empiric antibiotics promptly and avoid delaying them for LP logistics.
ADVICE

Reserve CT Before LP For High-Risk Signs

  • Do not reflexively get head CT before LP; reserve CT for specific risk factors (immunocompromise, focal deficits, papilledema).
  • If no risk factors exist, perform LP promptly rather than delay for imaging.
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