This Week in Neuroscience TWiN 44: ADHD and persistent pain
Nov 2, 2023
TWiN reviews a mouse model of ADHD and its hypersensitivity to pain. They explore the comorbidity between ADHD and autism, the use of stimulants for treatment, and the impact of inflammatory conditions. Methylphenidate helps with reducing hyperactivity but not pain hypersensitivity. They discuss the challenges and data richness in testing attention and response control in mice/rats. ADHD affects task performance and daily activities but medication and motivation can have positive effects. ADHD mice show heightened pain sensitivity and the no-cebo effect may play a role.
Chapters
Transcript
Episode notes
1 2 3 4 5 6 7 8
Introduction
00:00 • 3min
Exploring the Biological Basis of Sensitivity and Comorbidity between ADHD and Autism
02:58 • 9min
Investigating the Response to Painful Stimuli and Inflammatory Conditions in ADHD
12:22 • 6min
Methylphenidate's Effects on Pain Sensitivity in Mice with ADHD
17:54 • 27min
Examining Attention and Response in Mice or Rats
44:51 • 2min
The Impact of ADHD on Task Performance and Daily Activities
46:37 • 4min
Investigating Pain Sensing in ADHD Mice
51:00 • 2min
Exploring the Role of the No-cebo Effect and ADHD in Pain Sensation
52:57 • 8min