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TWiN 44: ADHD and persistent pain

This Week in Neuroscience

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Methylphenidate's Effects on Pain Sensitivity in Mice with ADHD

The speakers explore the use of methylphenidate (Ritalin) to address pain sensitivity in mice with ADHD, discussing previous studies that show its effectiveness in reducing hyperactivity. They find that while methylphenidate helps with reducing hyperactivity, it does not alleviate pain hypersensitivity in the mice. The chapter also delves into the distribution of synaptic proteins associated with excitatory or inhibitory synapses in the spinal cord and discusses experiments related to pain and ADHD.

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