Complex Systems with Patrick McKenzie (patio11) The future of pandemic preparedness, with Joshua Morrison
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Dec 19, 2024 Joshua Morrison, CEO of 1Day Sooner and advocate for scientific advances in infectious disease response, joins the conversation. He shares insights on the successes and failures of Operation Warp Speed in vaccine development. Morrison highlights the need for innovative clean air technologies to improve pandemic preparedness and discusses the importance of effective communication and trust in public health. The conversation also touches on leveraging past experiences to enhance regulatory frameworks for rapid response to future pandemics.
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Operation Warp Speed's Portfolio Approach
- Operation Warp Speed involved the US government funding multiple vaccine candidates.
- This diversified risk and increased the likelihood of a successful vaccine by the end of 2020.
Prehistory and Pull Funding of Warp Speed
- Operation Warp Speed's success was partly due to prior work on mRNA vaccine platforms and viral vector platforms.
- The government also used "pull funding", guaranteeing purchase of approved vaccines, which incentivized development.
mRNA Vaccines vs. Traditional Vaccines
- Traditional vaccines use weakened or parts of viruses to stimulate immunity, while mRNA vaccines use a novel approach.
- mRNA vaccines stimulate the immune system to produce antibodies without using any virus.