The PedsDocTalk Podcast: Child Health, Development & Parenting—From a Pediatrician Mom Autism: Is Tylenol to Blame? Is Leucovorin the Answer? A conversation with a fellow pediatrician and developmental behavioral pediatrician
Oct 15, 2025
Join Dr. Anshu Batra, a seasoned developmental-behavioral pediatrician, and Dr. Tanya Altmann, founder of Calabasas Pediatrics, as they delve into the complexities of autism. They clarify misconceptions surrounding Tylenol's link to autism and discuss the potential of leucovorin, emphasizing it's not a cure but may aid some children. The episode also highlights the role of genetics, the impact of screen time on young minds, and the importance of micronutrients in development. Their insights invite empathy and a deeper understanding of autism.
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Correlation Isn’t Causation For Tylenol
- Observational studies linking acetaminophen to autism show correlation but not causation.
- Sibling-comparison studies failed to show a direct causal link, so Tylenol is not proven to cause autism.
Autism Is Multifactorial With Strong Genetics
- Autism is highly multifactorial with genetics playing the largest role.
- Environmental factors (age, toxins, infections, prematurity) interact with genetics to influence risk.
Try Leucovorin As A Targeted Trial
- Consider leucovorin (folinic acid) as a trial for some children with neurodevelopmental issues.
- Use it selectively because studies show benefit in some kids but it's not a universal cure.
