Neurology® Podcast
Epilepsy in Patients With Primary CNS Lymphoma
Oct 17, 2024
Dr. Oumaima Aboubakr, a neuro-oncologist specializing in primary CNS lymphoma and epilepsy, shares vital insights on the surprising prevalence of seizures in these patients, noting that 25% experience them. She discusses how seizures can signal tumor activity and impact disease progression and prognosis. Aboubakr emphasizes the need for careful monitoring and adaptable treatment plans to manage seizure activity effectively. Her analysis urges healthcare professionals to deepen their understanding of seizure risks associated with CNS lymphoma.
12:19
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Quick takeaways
- Epilepsy is prevalent in primary CNS lymphoma patients, with one in four affected, challenging previous beliefs about its rarity.
- Seizures, while not directly linked to overall survival, indicate shorter progression-free survival periods and necessitate vigilant monitoring for disease activity.
Deep dives
Prevalence of Epilepsy in CNS Lymphoma Patients
Epilepsy is more common in patients with primary central nervous system lymphoma than previously thought, with one in four experiencing seizures at some point during their illness. This finding contradicts the belief in the neuro-oncology community that seizures are rare in these patients. Seizures can occur either as an initial symptom or develop later, indicating tumor activity. The study highlights the necessity for clinicians to reassess their understanding of seizure risk in this patient population and to monitor accordingly.
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