Optimal Health Daily - Fitness and Nutrition

3044: Pernicious Anemia and Shots vs Supplements - The Importance of the B12 Vitamin

Jul 11, 2025
Dive into the world of pernicious anemia and its impact on vitamin B12 absorption. Learn how this autoimmune condition poses health risks and why managing it effectively is crucial. Discover the debate between B12 injections and supplements, with evidence suggesting injections are usually more reliable. The podcast also emphasizes the significance of vitamin B12 for various populations, especially the elderly and those on plant-based diets, urging listeners to consult healthcare professionals for proper management.
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INSIGHT

Understanding Pernicious Anemia

  • Pernicious anemia is an autoimmune condition blocking intrinsic factor, essential for B12 absorption.
  • Without intrinsic factor, the body can't absorb B12, leading to unhealthy red blood cells and nerve damage.
INSIGHT

Who Is at Risk of B12 Deficiency

  • Vitamin B12 deficiency risk increases with age, vegetarian or vegan diets, digestive disorders, and some medications.
  • Most active B12 comes from animal products; plant-based sources are usually not bioavailable forms.
ADVICE

B12 Shots vs Supplements

  • For pernicious anemia, B12 injections are recommended as they bypass absorption issues.
  • High-dose oral B12 (1,000–2,000 mcg daily) might help but should be discussed with a doctor.
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