

E194: Better than the sum of its parts: Whole Blood In Trauma: W/ Dr. Zaffer Qasim
7 snips Jun 17, 2021
Dr. Zaffer Qasim, an emergency and critical care physician from Philadelphia, dives into the revolutionary use of whole blood in trauma resuscitation. He discusses its advantages over traditional component transfusions, emphasizing historical context and current research. Dr. Qasim highlights how this approach could significantly improve survival rates in both military and civilian trauma cases. This engaging conversation sheds light on a critical advancement in pre-hospital and emergency medicine that could reshape trauma care.
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Hemorrhage Remains Leading Preventable Killer
- Hemorrhage accounts for a large share of potentially preventable deaths in military and civilian trauma studies.
- Zaffer Qasim emphasizes delays from injury to definitive hemorrhage control as a major driver of those deaths.
Hemorrhage Creates A Coagulopathy Cascade
- Hemorrhage triggers endotheliopathy, malperfusion-driven acidosis, consumption of clotting factors, and hypothermia that worsen coagulopathy.
- Zaffer Qasim explains these interacting processes magnify bleeding and complicate resuscitation.
Avoid Crystalloids For Severe Hemorrhage
- Avoid large-volume crystalloids in hemorrhagic shock because they worsen hypothermia, acidosis, and dilute coagulation factors.
- Zaffer Qasim recommends early use of blood products rather than cold, acidic crystalloids for resuscitation.