Dr Ford Brewer - PrevMed
An OLD Drug that Stops Heart Attacks - Ford Brewer MD MPH - PrevMed Health
Apr 14, 2025
Discover how colchicine, an old drug, is making waves in lowering cardiovascular risk and preventing heart attacks. The discussion emphasizes the critical link between inflammation and heart health. Personalized treatment emerges as a key trend, allowing tailored strategies for diabetes and individual risk factors. The alarming statistics reveal a hidden crisis in cardiovascular health, with heart attacks and strokes affecting countless lives, drawing attention to the need for better prevention and management of metabolic diseases.
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Quick takeaways
- Colchicine significantly reduces cardiovascular disease events but remains underutilized due to common gastrointestinal side effects and medical reluctance.
- Recent research emphasizes inflammation's role in heart disease, suggesting a shift in focus from LDL cholesterol to anti-inflammatory treatments like colchicine for prevention.
Deep dives
The Role of Colchicine in Cardiovascular Health
Colchicine has been shown to decrease cardiovascular disease events, helping to lower the risk of heart attacks and strokes. Studies indicated a significant reduction in cardiovascular events among patients with stable atherosclerosis and those who had experienced a recent heart attack. Despite its effectiveness, colchicine is often underutilized due to common side effects like gastrointestinal distress, including diarrhea and nausea, which affect up to 75% of users. Barriers also exist due to the reluctance of the medical community to embrace colchicine after years of preference for more established treatments.
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