Cell & Gene: The Podcast Improving TCR T-Cell Persistence and Efficacy with Adaptimmune's Dennis Williams
Nov 7, 2024
Dennis Williams, Senior Vice President of Late Stage Development at Adaptimmune, dives into the revolutionary world of TCR T-cell therapies. He shares insights on the TECELRA trial, which achieved FDA approval for Tecelra, a groundbreaking engineered T-cell therapy for solid tumors. The conversation highlights the intricacies of developing therapies for synovial sarcoma and the unique challenges in this field. Williams also compares TCR and CAR T-cell therapies, shedding light on their distinct advantages and the complexities of off-target effects in treatment.
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