4min chapter

Cell & Gene: The Podcast cover image

Improving TCR T-Cell Persistence and Efficacy with Adaptimmune's Dennis Williams

Cell & Gene: The Podcast

CHAPTER

Navigating Off-Target Effects in TCR Therapies

This chapter explores the challenges and complexities of off-target effects in TCR and T-cell therapies, stressing the need for thorough preclinical testing. The discussion balances the potency against cancer cells versus the risk of toxicity to healthy tissues, emphasizing real-world implications in clinical trials.

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