Improving TCR T-Cell Persistence and Efficacy with Adaptimmune's Dennis Williams
Cell & Gene: The Podcast
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Navigating Off-Target Effects in TCR Therapies
This chapter explores the challenges and complexities of off-target effects in TCR and T-cell therapies, stressing the need for thorough preclinical testing. The discussion balances the potency against cancer cells versus the risk of toxicity to healthy tissues, emphasizing real-world implications in clinical trials.
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