Today in Focus What happens when you stop weight loss jabs?
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Sep 22, 2025 
Ian Sample, Science editor at The Guardian, breaks down how GLP-1 drugs function and the alarming rise in their costs. He shares insights on their origins and the implications for those reliant on them. Amy Young, a career coach from Kent, recounts her personal journey with the weight-loss drug Mounjaro, detailing the effects on her appetite and the challenges of stopping it. Both emphasize the need for better support systems for individuals facing the abrupt discontinuation of these medications.
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Rapid Weight Loss On Manjaro
- Amy Young was prescribed Manjaro privately and lost three and a half stone (23 kg) in eight months.
- She planned to stay on it until reaching her goal but an unexpected price rise forced a decision to stop.
Sudden Price Hike Forced Cold Turkey
- Amy received three days' notice that her provider would switch her to a cheaper drug or charge ~£310 to stay on Manjaro.
- She says providers gave no guidance on how to stop and many people felt abandoned and had to go cold turkey.
Food Noise Vanished On Treatment
- Amy described losing appetite and 'food noise' on the drug, sometimes skipping meals and having very light lunches.
- She welcomed the relief from decision fatigue about food and reported improved food choices.