Founder's Journal

How to Become Relentless as an Entrepreneur (Kian Sadeghi, Nucleus)

10 snips
May 28, 2024
Kian Sadeghi, founder of Nucleus, shares his journey from dropping out of UPenn to building a genetic testing company. He discusses the importance of relentlessness, talent identification, personal tragedy inspiring genomics, and embracing fear and self-belief in entrepreneurship.
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ANECDOTE

Tragedy Sparks Interest

  • Kian Sadeghi's cousin tragically died in her sleep, attributed to "bad genetics".
  • This sparked his interest in genetics, leading him to a DIY gene-editing lab in Brooklyn.
INSIGHT

Programming's Advantage

  • Kian realized that programming's iterative nature made it faster for experimentation than biology.
  • This led him to study computational biology, combining programming, statistics, and genetics.
ANECDOTE

Vision for Nucleus

  • In a lecture on decreasing genome sequencing costs, Kian foresaw the need for an application layer for DNA.
  • This inspired him to start Nucleus, envisioning a human genome on every smartphone.
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