Peptides and Longevity: Redefining Aging and Transforming Health with Dr. Kent Holtorf

The Ultimate Peptide Cheat Sheet: Everything You Need to Know to Master Your Health

Aug 13, 2025
Dr. Kathleen O’Neil-Smith, a physician and researcher specializing in peptides and regenerative medicine, joins in to discuss their transformative power. She shares insights on using peptides for pain relief, brain injury recovery, and immune balance. Highlighting real-world cases, she explains how specific peptides target various health issues, including joint degeneration and gut health. Kathleen also recounts her personal experience with peptides in restoring her son’s health after a traumatic brain injury, emphasizing tailored protocols for optimal recovery.
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ADVICE

Combine Local Injections With IV Support

  • For joint pain, combine targeted peptides with lubricants and platelet-rich plasma for local repair.
  • Inject AOD (growth-hormone fragment) with hyaluronan and consider IV BPC/PRP for systemic inflammation control.
INSIGHT

Fascia Is A Signaling Network

  • Fascia is an interconnected, signaling-rich network that transmits pain and function across the body.
  • Treating fascia (not just deep joints) can resolve pain appearing in distant areas because fascia links tissues systemically.
ADVICE

Use Small Local Peptide Doses For Soft Tissue

  • For soft-tissue inflammatory pain (e.g., polymyalgia), use small local peptide doses plus physical manipulation.
  • Try thymosin alpha-1 and thymosin beta-4 in soft tissue to quickly restore movement and reduce inflammation.
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