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Why do some men get ill after they orgasm?

Apr 28, 2025
The podcast dives into the surprising and uncharted territory of Post-Orgasmic Illness Syndrome (POIS). Explore how this rare condition impacts men with symptoms that can be debilitating after orgasm. With only a handful of cases documented, the discussion raises questions about its true prevalence and the challenges in diagnosing and treating it. Get ready for intriguing insights into a topic that flips the script on misconceptions about male sexuality.
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INSIGHT

Postorgasmic Illness Syndrome Symptoms

  • Postorgasmic Illness Syndrome (POIS) causes men to feel severe physical and mental symptoms after orgasm.
  • Symptoms include depression, headaches, sneezing, temperature changes and last 2-7 days.
INSIGHT

POIS Impact and Duration

  • POIS symptoms appear within 30 minutes of orgasm and last for days in over 90% of cases.
  • The condition severely affects patients' personal lives and relationships.
INSIGHT

POIS Causes and Treatments

  • The cause of POIS is uncertain but may involve autoimmune reactions or hormonal and brain chemical imbalances.
  • Research on treatments like antihistamines shows promise but remains inconclusive.
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