Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive into the world of diffused large B-cell lymphoma with special guest Dr. Carla Casulo from the Wilmot Cancer Institute in Rochester, New York.

Key Points Covered:
•⁠ ⁠Understanding the importance of accurate diagnosis through excisional biopsy in diffused large B-cell lymphoma.
•⁠ ⁠Exploring the significance of cell of origin in guiding treatment decisions.
•⁠ ⁠Initial treatment approaches for stage 1 and 2 disease, including the use of Polatuzumab based on the POLARIX trial.
•⁠ ⁠Treatment options for relapsed or refractory disease, including CAR-T therapy, BiTE therapy, and anti-CD19 antibody agents.
•⁠ ⁠Managing toxicities associated with different treatment regimens, such as cytopenias, infections, and neurotoxicity.

Join us as we unravel the complexities of diffused large B-cell lymphoma and discuss the latest advancements in treatment options with Dr. Carla Casulo. Stay informed and up to date with the Oncology Brothers podcast!

Don't forget to like, share, and subscribe for more insightful discussions on oncology topics. Thank you for tuning in to the Oncology Brothers podcast.

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