This Podcast for the Neurology Journal begins and closes with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interview Dr. Russell Swerdlow about his paper on frontotemporal dementia. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Amphysin antibody-associated stiff-person syndrome. The podcast concludes where Dr. Thomas Wingo interviews Dr. John Trojanowski about TAR DNA-binding protein (TDP-43) for the Lesson of the Week segment. The participants had nothing to disclose.