The Curious Clinicians

58 - Gutting a Pearl

Oct 1, 2022
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INSIGHT

Furosemide Absorption

  • Furosemide's poor absorption in heart failure is a clinical pearl.
  • Gut edema is wrongly assumed to be the cause.
INSIGHT

Furosemide Bioavailability

  • Furosemide absorption varies, from 10% to 100%.
  • This variability exists between and within patients, even without heart failure.
INSIGHT

Absorption Site

  • Furosemide is absorbed in the stomach and small bowel.
  • Duodenal absorption is thought to be more significant.
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