That Paleo Show

TPS 75: Dr. Jack Kruse Talks Leptin Reset, Epi-Paleo Rx And Some Serious Bio Hacking

Jul 11, 2014
Dr. Jack Kruse, a respected neurosurgeon and CEO of Optimized Life, shares his personal health journey and innovative approaches to weight loss and wellness. He discusses the connection between brain inflammation and obesity, revealing his groundbreaking leptin protocol. Kruse advocates for a high-fat seafood diet, particularly oysters, and cold thermogenesis for hormone balance. He also highlights the impact of water health and climate on food sources in Australia, urging for urgent solutions to these environmental challenges.
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ANECDOTE

Jack's Personal Weight Loss Journey

  • Jack Kruse was 6'2" and 357 pounds as a neurosurgeon at 40 years old and struggled with weight loss despite conventional advice.
  • After studying medical literature, he applied new principles, losing 133 pounds in 11 months and inspiring family members to do the same.
ADVICE

Fix Obesity by Boosting Electrons

  • To fix obesity, address NAD+ deficiency through a ketogenic diet rich in DHA from real seafood like oysters.
  • Understand food's electron role in mitochondrial function and avoid calorie-only thinking for effective weight loss.
ADVICE

Leptin Reset Protocol Advice

  • Determine if you're leptin-resistant using six steps from Jack's blog before starting his protocols.
  • Start with a big breakfast (50-75g protein or fat) for 4-6 weeks to reset leptin before progressing to cold thermogenesis.
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