Neurology® Podcast Understanding Acute Symptomatic Seizures
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Nov 28, 2024 Dr. Vineet Punia, a neurologist at the Cleveland Clinic specializing in anti-seizure medication research, joins to discuss the complexities surrounding acute symptomatic seizures. He highlights how the prescribing practices vary and often don’t lead to improved outcomes for patients at discharge. The conversation delves into the impact of seizure type, brain injury causes, and the role of continuous EEG monitoring. Punia emphasizes the need for personalized treatment plans and the emotional challenges caregivers face in managing these patients.
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ASM Impact on Outcomes
- Anti-seizure medications (ASMs) do not improve functional outcomes for acute symptomatic seizure patients.
- This finding applies to both discharge and three-month follow-up, according to a study.
Factors Influencing ASM Prescription
- Several factors influence ASM prescription: clinical/electrographic seizures, rhythmic/periodic patterns, and etiology.
- Location and care team also play a role, with neuro ICU admissions and neurology team involvement increasing ASM use.
Discharge on ASM
- Acute symptomatic seizures, rhythmic/periodic discharges, and etiology are independent risk factors for discharge on ASM.
- 10% of patients without seizures or concerning patterns are still discharged on ASM due to etiology.