This Podcast for the Neurology Journal begins and closes with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Aman Savani interview Drs. David Vaillancourt and Deborah Little about their paper on substantia nigra of de novo Parkinson disease. In the next segment, Dr. Ted Burns is reading our e-Pearl of the week about positive neuropathic sensory symptoms. Andy Imholte is announcing the launch of the new mobile site for AAN members. URL is m.AAN.com. The podcast concludes where Dr. Govind Nair interviews Dr. John Carew for the Lesson of the Week segment. The participants had nothing to disclose.