The HemOnc Pulse cover image

The HemOnc Pulse

Part One: The Question of MRD in CLL Therapy

Jul 18, 2024
The podcast features experts in CLL therapy discussing topics like the impact of MRD, comparative analysis of BTK inhibitors, challenges in defining cure, selecting BTKIs in frontline therapy, and optimizing treatment strategies for young CLL patients. They debate on therapy duration, patient outcomes, and future approaches in treating high-risk CLL patients.
35:34

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Quick takeaways

  • Consider patient selection criteria for CLL therapy options and the role of measurable residual disease (MRD) in treatment decisions.
  • Evaluate the selection of BTK inhibitors in CLL treatment based on factors like comorbidities, treatment responses, and treatment tolerability.

Deep dives

Unanswered Questions in CLL Therapy

The podcast episode delves into the unanswered questions surrounding chronic lymphocytic leukemia (CLL) therapy. Panelists discuss critical points such as patient selection criteria for different treatment options, the role of measurable residual disease (MRD) in treatment decisions, and the sequencing of therapies in CLL management. Specific areas of focus include time-limited therapy, the relevance of MRD, and the impact of therapy selection on long-term outcomes.

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