Challenges in Defining Cure and Treating High-risk Patients in CLL Therapy

Exploring the complexities of defining cure in CLL treatment, this chapter discusses the challenges in identifying high-risk patients and tailoring treatment strategies. From discussing specific mutations to ongoing trials with BTK and BCL2 inhibitors, the conversation touches on potential future approaches like cell therapy. Additionally, it debates on therapy duration, standard treatment options, and factors influencing treatment outcomes in high-risk CLL patients.