Annals On Call Podcast
A Resurgence of Dengue
May 6, 2024
Drs. Davidson Hamer and Ralph Huits discuss the resurgence of dengue fever, its clinical presentations, and advancements in vaccine strategies. They explore the complexities of dengue virus transmission, disease progression, management challenges, and compare it with chicken gania. The podcast also covers global outbreaks, genomics, vaccination complexities, and diagnostic approaches.
26:46
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Quick takeaways
- Differentiating dengue from chikungunya is crucial due to distinct clinical manifestations and risks of complications like bleeding.
- Genomic sequencing assists in understanding dengue variants, transmission dynamics, and informs future vaccination strategies.
Deep dives
Understanding Dengue and Its Presentation
Dengue, a prevalent arbovirus, is primarily transmitted by Aedes mosquitoes, leading to febrile illness with symptoms like rash, severe headaches, and flu-like syndrome. In severe cases, about 1 to 5% can experience organ dysfunction or bleeding. Prediction of severe cases remains challenging for clinicians due to the lack of effective antiviral treatments, emphasizing the importance of close monitoring and prudent fluid management.
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