Two Onc Docs Hepatocellular Carcinoma (HCC) 2025 UPDATE
May 12, 2025
Dive into the complexities of hepatocellular carcinoma, emphasizing the critical role of liver function evaluation. Discover the significance of the Child-Pugh score in staging HCC, and recent advancements in treatment options like immunotherapy and new medications. Learn about innovative strategies to enhance survival rates and tailor therapies based on individual patient needs. The discussion reveals insights on treatment-related risks, ensuring a well-rounded understanding for effective management of this challenging condition.
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Assess Liver Function with Child-Pugh
- Use the Child-Pugh score to assess liver functional reserve in HCC patients.
- Remember ABCDE: Albumin, Bilirubin, Coagulation (INR), Ascites, Encephalopathy for scoring.
Diagnose HCC Without Biopsy Often
- Diagnose HCC in cirrhotic patients using ultrasound screening every six months.
- Biopsy is required only for non-cirrhotic patients or uncertain imaging findings.
Stage HCC with Barcelona System
- Use the Barcelona Clinic Liver Cancer (BCLC) staging, combining tumor burden, liver function, and performance status.
- Provide best supportive care for terminal stage D patients with poor liver function and performance status.