Huberman Lab Essentials: Understanding & Conquering Depression
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Jul 3, 2025 Explore the intricate biology behind major depression, from neurotransmitters to genetic predispositions. Discover innovative treatments like ketamine and psilocybin that show promise in alleviating symptoms. Learn how nutrition and exercise, including supplements like omega-3s and creatine, can significantly improve mood. Uncover the impact of chronic inflammation and lifestyle changes on mental health. A compelling dive into both traditional and cutting-edge approaches to understanding and conquering depression awaits!
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Major Depression Symptoms Explained
- Major depression affects about 5% of the population and includes grief, sadness, and anhedonia.
- It also involves anti-self confabulation and vegetative symptoms like exhaustion and disrupted sleep.
Cortisol's Role in Depression
- Cortisol levels in depression are abnormally elevated at night instead of the morning.
- This altered cortisol rhythm and hormone disruption contribute to depressive symptoms.
Cold Exposure and Exercise Help
- Use cold exposure like cold showers to increase norepinephrine and potentially boost mood.
- Regular exercise releases norepinephrine, dopamine, and serotonin to help counteract depressive symptoms.