

The U.S.-Iran Escalation Explained 06/23/25
Jun 23, 2025
Retired U.S. Army Colonel Jack Jacobs, a Medal of Honor recipient and military strategy expert, discusses the U.S. military strikes on Iranian nuclear sites and potential repercussions for U.S.-Iran relations. Daniel O'Day, CEO of Gilead Sciences, shares insights on the FDA's approval of a groundbreaking injectable HIV prevention drug and its significance for public health. Both guests provide valuable perspectives on geopolitical tensions and innovations in healthcare, underscoring the interplay of politics and science.
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Impact of U.S. Strike on Iran Nuclear Site
- The U.S. strike degraded Iran's Fordow nuclear facility significantly, though exact damage remains unclear.
- Iran likely moved some fissile material earlier, but most was at Fordow during the attack.
Iran's Expected Retaliation Tactics
- Iran will likely focus on proxy and cyber attacks over direct assaults on U.S. troops to avoid devastating retaliation.
- The U.S. must monitor cyber threats and proxy activities, especially near American interests and Israel.
Iran Regime Change Realities
- Regime change in Iran is unlikely to be externally driven; only internal forces can cause political turnover.
- Military leadership might replace mullahs, changing approach without becoming more liberal.