Amos Hochstein, a former Biden senior advisor, shares insights on the fragile ceasefire in the Israel-Hamas conflict and the urgent humanitarian needs. Dr. Scott Gottlieb, former FDA commissioner, examines the alarming potential impacts of proposed NIH funding cuts on public health research. The conversation also touches on Elon Musk's ambitious $97.4 billion bid for OpenAI and tensions with CEO Sam Altman, and President Trump's pause on anti-bribery law enforcement, raising ethical concerns in international business.

Kevin Hassett, former Director of the National Economic Council, shares insight on President Trump's recent comments regarding Treasury irregularities and new tariffs on steel and aluminum. The discussion touches on the significant economic implications of these tariffs and the intertwined politics with billionaire influence. Alongside him, EDO CEO Kevin Krim highlights the Super Bowl's standout commercials, revealing how advertising impacts consumer behavior while analyzing both triumphant and controversial ads.

Lawmakers push for a ban on the Chinese AI app DeepSeek on government devices, citing national security risks. Meanwhile, a federal judge halts the Trump administration's buyout offer for federal workers, raising concerns about employee morale. Union leader Everett Kelley critiques Elon Musk's budget cuts, suggesting there are better alternatives. The economy shows signs of strength with 143,000 new jobs added, while a Treasury review assures it’s not politically biased. Discussions also highlight ongoing fears linked to tech app data security and its implications for Americans.

Rich Kleiman, Kevin Durant's longtime NBA agent and sports entrepreneur, talks about unique networking opportunities for NFL players around the Super Bowl, including insights on NBA trades and emerging competition in the league. Mick Mulvaney, former White House chief of staff, delves into the costs of government and Elon Musk's ambitious efficiency plans. The conversation touches on the interplay of sports, business, and legislation, enriching the dialogue with humor and economic insights.

Cathie Wood, CEO of ARK Invest, shares her visionary insights on the future of disruptive technologies like robotaxis and bitcoin. Jamil Ghani, Amazon Prime’s VP, discusses the impact of tariffs on Amazon's business and competitors. The conversation delves into the complexities of U.S.-China trade relations, the innovations driving the delivery industry, and the evolving landscape of AI in transportation. With a bullish perspective, Wood and Ghani explore how these trends could shape the economy in 2025 and beyond.

Kevin Hassett, former Director of the National Economic Council under President Trump, unveils the complexities of tariffs and their unexpected links to the fentanyl crisis. He argues these measures are more about a drug war than a trade war, sparking discussions on Canada’s potential retaliation. The episode also dives into the implications for the auto industry, global economic strategies, and how the tariff landscape influences public health issues. Insights from notable analysts further enrich the conversation.

Steve Liesman, a CNBC reporter specializing in economic analysis, discusses the implications of President Trump's tariffs on Canada and Mexico. Former FDA Commissioner Dr. Scott Gottlieb critiques Robert F. Kennedy Jr.'s understanding of healthcare during his challenging confirmation hearings. Mellody Hobson, co-CEO of Ariel Investments, speaks about the exciting investment landscape in women’s sports, particularly with the new National Women’s Soccer League franchise in Denver, advocating for diversity and inclusion in corporate leadership.

Jon Gray, President and COO of Blackstone, shares insights on the firm’s significant investments in AI infrastructure amidst impressive financial results. He highlights the impact of these investments on business productivity and the evolving landscape of employment due to AI advancements. Alongside aviation experts, the discussion delves into the tragic midair collision near the Potomac River, underlining the urgent need for improved airspace regulations and advanced AI tools to enhance aviation safety. It's a compelling blend of finance and critical current events.

Reid Hoffman, co-founder of LinkedIn and Inflection AI, dives into the heated AI race between the U.S. and China, spotlighting the disruptive power of China's DeepSeek. He discusses the complexities of the competitive landscape, including ethical dilemmas and the impact of open versus closed-source technologies. Hoffman's insights also touch on how political decisions intertwine with tech advancements, emphasizing the proactive role of innovation in shaping a better future.

Texas Senator Ted Cruz, chairman of the Committee on Commerce, Science and Transportation, discusses the geopolitical stakes surrounding the Panama Canal, including the implications of American control and China’s influence in the region. Joining him is Chris Hayes, who previews his book on the commodification of attention in the digital age. They explore how tech companies manipulate attention and the challenges this poses for society and democracy. The conversation also touches on recent political maneuvers and the ethical dilemmas of activist short selling.