
The Daily Marriage and Sex in the Age of Ozempic: An Update
141 snips
Dec 26, 2025 Lisa Miller, a health writer for The New York Times, delves into how GLP-1 weight-loss drugs like Ozempic have altered romantic relationships. She shares the story of Jean and Javier, high school sweethearts whose marriage faced challenges after Jean's 60-pound weight loss. As Jean embraces new boundaries and lifestyle changes, their intimacy shifts dramatically, sparking conflict over diverging routines. Their journey raises questions about empowerment and identity, ultimately leading to a surprising resurgence in their sexual relationship.
AI Snips
Chapters
Transcript
Episode notes
Rapid Weight Loss Changed Their Lives
- Jean lost 60 pounds on a GLP-1 drug within eight months and saw people treat her differently at work and in social settings.
- The rapid change unlocked new opportunities and shifted how colleagues and friends perceived her, which surprised both partners.
Medical Effects Ripple Into Life
- GLP-1 drugs suppress hunger and enable sustained weight loss while users remain on medication.
- That physiological control can cascade into nonmedical changes like job offers, social shifts, and relationship stress.
Lifestyle Shifts Sparked Major Conflict
- After losing weight, Jean stopped drinking and preferred quiet evenings, which clashed with Javier's outgoing habits.
- Their lifestyle changes produced loud, frequent fights and confusion about who they were as a couple.

