The Neuro Experience
What Are the 3 Key Blood Tests for Alzheimer's Detection? | A Woman’s Guide to Alzheimer’s Disease | Part 2
Mar 26, 2025
Alzheimer's disease is a slow, silent process that can begin decades before symptoms appear. The discussion dispels the myth that it’s purely genetic, highlighting the influence of the APOE4 gene coupled with lifestyle factors. Women, particularly post-menopause, face unique vulnerabilities. Listeners will learn about three innovative blood tests that can identify early signs of Alzheimer's. The conversation also covers essential prevention strategies, including managing blood sugar, hormones, and inflammation to protect cognitive health.
17:08
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Quick takeaways
- Alzheimer's risk is influenced more by lifestyle and metabolic health than genetics, challenging the common belief that it's purely hereditary.
- Three innovative blood tests—P-tau217, GFAP, and NFL—can detect early signs of Alzheimer's, enabling proactive health interventions long before symptoms appear.
Deep dives
The Genetic Misconception of Alzheimer's Disease
Alzheimer's disease is often perceived as purely genetic, but recent research indicates that genetics account for only a small fraction of cases. Approximately 1% to 3% of Alzheimer's instances arise from deterministic mutations in specific genes, which lead to early onset of the disease. Most Alzheimer's cases are influenced by a combination of genetics, lifestyle, and metabolic health, meaning that personal choices made over years play a significant role in the disease's development. This highlights the importance of understanding that while genetics can elevate risk, they do not dictate one's fate regarding Alzheimer's.
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