The Wellness Messiah Podcast How to MANIPULATE Growth Hormone With Food (Studies Show)
Nov 18, 2025
Explore the fascinating role of IGF-1 in aging and muscle growth. Discover how dietary protein directly influences IGF-1 levels, shaping bone density and longevity. Learn about the crucial 'sweet spot' for IGF-1 that balances health risks and benefits. Dive into the effects of calorie versus protein restriction and find out how adjusting protein intake can optimize IGF-1 for better health. Personal experimentation reveals intriguing insights into muscle gain strategies and the delicate balance needed for optimal health as we age.
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IGF-1 Controls Growth And Longevity
- IGF-1 is the main active growth factor derived from HGH and drives cell, muscle, bone growth and rejuvenation.
- Both low and high IGF-1 levels raise mortality risk, with ~120–160 ng/mL linked to lowest mortality.
Protein Signals The Body To Make IGF-1
- Dietary protein strongly stimulates IGF-1 production including bone-specific IGF-1 that signals bone building.
- Protein acts as a signal to make IGF-1 rather than just supplying raw material for tissues.
Calories Alone Don’t Lower IGF-1
- Human trials show calorie restriction alone did not lower serum IGF-1 unless protein was also reduced.
- Protein intake is a key determinant of circulating IGF-1 in humans, not calories alone.