Mitochondria: Your Guardians Against Inflammation - AI Podcast

Mitochondria and Immune Function

Mitochondria play a crucial role in regulating inflammation through their interaction with macrophages, which are immune cells responsible for clearing pathogens from the body. Together, they produce interleukin-10 (IL-10), a vital anti-inflammatory signaling molecule that instructs the immune system to halt its response once a threat is neutralized. This collaboration is essential, as the absence of IL-10 can lead to chronic inflammation, contributing to autoimmune disorders like rheumatoid arthritis and lupus. The signaling process is initiated by superoxide molecules generated within the mitochondria, emphasizing that mitochondria are not only energy producers but also key players in modulating immune responses and controlling inflammation levels in the body.