

Episode 451: Everything About Exercise
Aug 12, 2025
Dive into the essentials of exercise, revealing how it safeguards your heart, brain, and longevity. Learn the magic number of 150+ minutes of movement a week. Discover intriguing studies linking coffee to blood pressure and the brain-boosting benefits of vitamin B3 and green tea. Unpack the potential of semaglutide in reversing aging and the MVX test predicting mortality risk. Plus, explore the surprising diabetes connection with french fries, the role of CoQ10, and how olive oil can enhance cholesterol. Exercise is truly a game changer!
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Use A Paper Filter For Coffee
- Use an organic paper filter in drip coffee makers to reduce unwanted compounds from coffee oils.
- Dr. Joel Kahn recommends filtered coffee and reassures habitual drinkers about modest blood pressure effects.
Coffee May Slightly Lower Blood Pressure
- A Mendelian randomization study found habitual coffee drinkers had ~3 mmHg lower systolic and ~2 mmHg lower diastolic blood pressure.
- The finding came from a large Biobank analysis of regular (not decaf) coffee consumption.
Semaglutide Linked To Slower Epigenetic Aging
- A randomized trial reported weekly semaglutide injections slowed epigenetic aging and reversed measured biological age by about 3.1 years.
- The trial was small and conducted in people with HIV, so results may not generalize broadly.