Jay Sanguinetti is a neuroscientist and meditation teacher at the University of Arizona, where he leads SEMA Lab, the Science Enhanced Mindful Awareness Lab. Trained in philosophy, neuroscience, and cognitive psychology, he completed his doctorate on conscious and unconscious visual perception. His consciousness research explores how focused ultrasound can augment meditation practice and make its benefits accessible to more people.
In this episode, we dig into why up to 98 percent of people abandon meditation apps within a month and what actually makes practice stick. Jay explains equanimity, the quality that keeps difficult emotions from getting stuck in your system, and why training it first changes everything. We explore how focused ultrasound gently tunes the brain compared to psychedelic states, the third wave of mental health, and how AI could support inner work and integration. This conversation is for anyone serious about personal transformation who wants the science behind contemplative practice.
Who This Episode Is For:
- Founders and CEOs who keep starting and stopping meditation
- Anyone curious about consciousness science and neurotech
- People exploring safer paths to inner transformation
What You'll Learn:
- Why equanimity is the foundation that makes meditation stick
- How focused ultrasound compares to psychedelics for tuning the brain
- Why technology should be measured by connection, not engagement
- What the third wave of mental health means for human potential
For full show notes: https://podcast.scottbritton.me/p/the-science-of-equanimity-and-its
Go Deeper:
If this conversation resonated, you can check out:
• Join my email list for ongoing insights on consciousness, spirituality, using business as a spiritual path and human potential.
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Chapters:
(00:00) Inside SEMA Lab and the science of mindfulness
(05:27) Equanimity explained and why meditation finally sticks
(10:23) Focused ultrasound versus psychedelics for tuning the brain
(16:36) How this technology reaches doctors and the public
(25:19) AI as a companion for integration and inner work
(43:01) The real test of technology is human connection
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