Bloody Minded Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview
Aug 6, 2024
Dive into the fascinating world of blood and discover its essential roles beyond mere sustenance. Learn about the mysterious origins of blood cells and their differentiation, revealing the complexities of hematopoiesis. Unpack the significance of red blood cells, their incredible lifecycle, and the crucial ingredients needed for their creation, including iron and vitamin B12. Explore the implications of nutrient deficiencies and their connections to anemia. It's a deep yet engaging exploration that educates while keeping it lively and fun!
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Blood Cell Origins Explained
- All blood cells originate from hematopoietic stem cells in bone marrow through hematopoiesis.
- Mature blood cells lose the capacity for self-renewal, except some lymphocytes and cancer cells.
Bone Marrow's Extraordinary Output
- Bone marrow produces about 10 billion red cells every hour and up to a billion white cells.
- Production scales up drastically during infection to meet increased demand.
White Cell Types & Functions
- White cells include granulocytes like neutrophils, eosinophils, basophils, and mast cells.
- Neutrophils are critical for innate immunity and have a short five-day lifespan in circulation.