Nobel Prize-winning biologist Venki Ramakrishnan discusses the new science of aging and the quest for immortality. Topics include molecular biology advancements, extending human lifespan, pioneering discoveries in dementia research, and anti-aging compounds.
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Quick takeaways
Understanding aging processes may lead to longer human lives by combating fear of death and loss of function.
Variability in lifespans among species shows potential for defying natural lifespan limits through biological alterations and resets.
Deep dives
Challenging the Inevitability of Death
The podcast explores how the inevitability of human mortality is being questioned by scientists studying human longevity. Venki Ramakrishnan, a Nobel Prize-winning molecular biologist, delves into the research outlined in his book 'Why We Die, the New Science of Aging and the Quest for Immortality.' He notes the anxiety surrounding mortality that humans experience, driven by a unique consciousness of our limited lifespan. The discussion highlights that the fear of death is intertwined with the loss of consciousness and individual function, rather than merely cellular turnover. Scientists propose that understanding aging processes may pave the way for longer and healthier human lives.
Advances and Limits in Lifespan Studies
The podcast delves into the variability of lifespans among species and the evolutionary factors influencing longevity. It explains how evolutionary optimization aims to maximize an organism's ability to pass on its genes, with larger animals typically living longer. While human life expectancy has doubled due to advancements in medicine, there seems to be a natural limit to lifespan around 120 years. The podcast mentions the possibilities of defying this limit through biological alterations and resets, drawing comparisons to species like hydras and jellyfish that exhibit age-reversing capabilities. From studying DNA damage to identifying compounds like Rapa Mysen, researchers are delving into diverse areas to combat aging and promote longevity.
Nobel Prize-winning molecular biologist Venki Ramakrishnan walks us through the ongoing revolution in biology that could allow us to live for a very, very long time.