

Muscle Growth Myths Destroyed by Top Researcher #385
Aug 3, 2025
In this insightful discussion, Eduardo De Souza, a top hypertrophy researcher and professor at the University of Tampa, shares his expertise on muscle growth measurement. He reveals why MRI is the gold standard and the limitations of ultrasound. The impact of aging on muscle quality is explored, highlighting the need for resistance training in older adults. They debunk myths about training volume, discuss the balance between anabolism and catabolism, and delve into genetics and recovery. The conversation is a treasure trove for anyone serious about optimizing their training.
AI Snips
Chapters
Transcript
Episode notes
MRI Gold Standard for Hypertrophy
- MRI remains the gold standard for measuring muscle hypertrophy with clear muscle cross-sectional imaging.
- Ultrasound is a valid cheaper alternative but often less accessible than ideal.
Understanding Hypertrophy Types
- Muscle hypertrophy includes myofibrillar (contractile protein) and sarcoplasmic (fluid and energy storage) growth.
- Sarcoplasmic hypertrophy contributes less and is tricky to isolate separately.
Muscle Growth in Length and Width
- Muscles grow both by adding sarcomeres in parallel and in series, especially in pennate muscles.
- Fascicle length increases, tendon angle changes to accommodate growth in length and thickness.